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Predicting Angioembolization Failure in Blunt Splenic Trauma.

Melissa A Kendall1, Tyler Zander1, Emily A Grimsley1

  • 1Department of Surgery, University of South Florida, Tampa, Fl, USA.

The American Surgeon
|November 14, 2025
PubMed
Summary
This summary is machine-generated.

Splenic artery angioembolization (SAAE) failure in high-grade blunt splenic injuries is predicted by red blood cell transfusion volume, systolic blood pressure, and injury severity. These factors help identify patients needing further intervention.

Keywords:
AngioembolizationSolid Organ InjuryTrauma

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Area of Science:

  • Trauma Surgery
  • Interventional Radiology
  • Emergency Medicine

Background:

  • Splenic artery angioembolization (SAAE) is a key treatment for high-grade blunt splenic injuries.
  • Nonoperative management is preferred, but SAAE failure necessitates further intervention.

Purpose of the Study:

  • To determine the failure rates of SAAE in blunt splenic injuries.
  • To identify predictive factors for SAAE failure (F-EMBO).

Main Methods:

  • Retrospective review of the TQIP database (2018-2022).
  • Inclusion of adult patients with AAST Grade III-V blunt splenic injuries undergoing SAAE within 24 hours.
  • Definition of F-EMBO as requiring splenectomy within 4 days or repeat SAAE.
  • Utilized univariable analysis and a gradient boosting machine model with SHAP for predictive factor identification.

Main Results:

  • Out of 6055 patients, 6.0% experienced F-EMBO (2.8% required splenectomy, 3.4% repeat SAAE).
  • F-EMBO patients had higher rates of anticoagulation, cirrhosis, lower systolic blood pressure, higher pulse rates, and greater red blood cell (RBC) transfusion requirements.
  • F-EMBO was associated with increased mortality, complications, longer hospital stays, and nonhome discharge rates.

Conclusions:

  • Red blood cell transfusion volume, systolic blood pressure, injury severity score, age, and pulse rate are significant predictors of SAAE failure.
  • These factors can guide clinical decision-making and resource allocation for patients with high-grade blunt splenic injuries.