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Updated: Jan 11, 2026

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
Application of AI-assisted magnifying colonoscopy system in the diagnosis of colorectal tumors: a multicenter
Xiaofei Fan1, Ayixie Maihemuti1, Xiaohan Cai1
1Department of Gastroenterology, Tianjin Medicaal University General Hospital, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Background:
Magnifying endoscopy is a reliable method for the differential diagnosis of colorectal tumors due to its high resolution and enhanced contrast, which allow for more precise detection and characterization. However, accurate assessment of tumor differentiation still requires significant expertise. To address this, we developed an AI-assisted diagnosis model (AADM) based on the Japan NBI Expert Team (JNET) classification and evaluated its diagnostic performance in comparison to endoscopists with varying levels of experience.
Methods:
A total of 2645 magnified images from 219 patients were collected for training and testing the model. The study employed an improved DeepLabV3 + model, a deep learning network that combines an encoder-decoder architecture with Atrous Spatial Pyramid Pooling (ASPP). We compared the model with six endoscopists with varying experience.
Results:
The AADM achieved an accuracy of 0.938 (Macro/Micro-average), with type-specific accuracies of 0.978 for Type 1, 0.891 for Type 2A, 0.912 for Type 2B, and 0.971 for Type 3. Sensitivity was 0.915/0.876 (Macro/Micro-average), and specificity was 0.954/0.959 (Macro/Micro-average). The area under the receiver operating characteristic curve (AUC) was 0.935/0.917 (Macro/Micro-average). The diagnostic performance of the AADM was superior to that of junior endoscopists (accuracy: 0.938 vs. 0.866, P < 0.05) and comparable to senior endoscopists (accuracy: 0.938 vs. 0.937, P > 0.05). Additionally, junior endoscopists significantly improved their accuracy from 0.866 to 0.951 after receiving assistance from the AADM (P < 0.01).
Conclusion:
The AADM demonstrated good diagnostic capability for JNET classification, facilitating more convenient and accurate diagnoses of colorectal tumors. AADM shows potential for optimizing surgical approach selection in colorectal tumor management. Further studies are needed to assess its effectiveness and cost-efficiency in real-world clinical settings.
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