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Published on: November 8, 2019
Computational Fluid Dynamics in Predicting Renal Malperfusion After Aortic Dissection Repair
Chengwei Yang1, Shujing Shao2, Xiaochang Leng2
1Department of Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Department of Imaging and Interventional Radiology, DeltaHealth Hospital Shanghai, Shanghai, China.
Background:
Renal atrophy following aortic repair is difficult to be identified through renal function biochemical measures due to compensation. Computational fluid dynamics (CFD) analysis is a promising approach for identifying anomalies of renal blood supply, which is related to renal atrophy.
Case Summary:
This study reports 3 patients who underwent renal atrophy after aortic repair during follow-up. The hemodynamics of renal arteries in each case was analyzed through employing the CFD method. The pressure ratio (PR; renal artery-to-aorta) measurements revealed significantly lower values on the atrophic side of the renal artery when comparing to the nonatrophic side.
Discussion:
PR is promising to serve as an early quantitative indicator, with persistent depression prior to obvious morphological atrophy. Serial CFD-based PR assessments show promise in predicting the risk of renal atrophy and facilitating earlier intervention.
Take-Home Message:
Patient-specific CFD simulations based on computed tomography angiography offer hemodynamic profiling to detect perfusion compromise in the preclinical phases.
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