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Ameboid cell inchworming: An adaptive phenotype triggered by abiotic-like stress
Víctor Herrera-Fernández1, Markus Hengstschläger2, Alexis J Lomakin1
1Center for Pathobiochemistry & Genetics, Institute of Medical Chemistry and Pathobiochemistry, Medical University of Vienna, Vienna, Austria; Center for Pathobiochemistry & Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
None:
Cells in motion must adapt their migratory strategies to diverse environmental stresses. In this issue of Developmental Cell, Yu et al. identify an evolutionarily conserved, switch-like phenotypic transition to inchworm migration in amoeboid cells encountering super-sticky microenvironments.
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