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Related Concept Videos

Common Respiratory Disorders01:31

Common Respiratory Disorders

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Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
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Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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Upper Respiratory Drugs: Decongestants01:27

Upper Respiratory Drugs: Decongestants

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Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...
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Upper Respiratory Drugs: First and Second-Generation Antihistamines01:15

Upper Respiratory Drugs: First and Second-Generation Antihistamines

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Antihistamines are a class of drugs widely used to alleviate the symptoms of allergies, such as sneezing, itching, and nasal congestion. They work by inhibiting the actions of histamine, which is released by immune cells in response to allergenic substances or tissue injuries.
Histamine binds to specific receptor sites, known as H1 receptors, on tissue cells, triggering inflammation and swelling. Antihistamines combat these effects by competing with histamine for these receptor sites. By...
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Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

609
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
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Chronic Pharyngitis01:23

Chronic Pharyngitis

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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
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Updated: Jan 10, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
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An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

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Respiratory syncytial virus-induced uvulitis.

Heather Forbes1, Anthony Acosta, Zane Elfessi

  • 1At Jesse Brown Veterans Affairs Medical Center in Chicago, IL, Heather Forbes works in the ED, Anthony Acosta is an emergency medicine physician, and Zane Elfessi is an emergency medicine pharmacy specialist. Z. Elfessi is also a clinical professor at the University of Illinois Chicago Retzky College of Pharmacy. The authors have disclosed no potential conflicts of interest, financial or otherwise.

JAAPA : Official Journal of the American Academy of Physician Assistants
|November 20, 2025
PubMed
Summary
This summary is machine-generated.

Respiratory syncytial virus (RSV) can cause serious complications in older adults, leading to emergency department visits. This case study highlights a rare instance of RSV-induced uvulitis, a condition not previously documented.

Keywords:
RSVangioedemacommon coldrhinorrheasore throatuvulitis

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Area of Science:

  • Medicine
  • Virology
  • Immunology

Background:

  • Respiratory syncytial virus (RSV) is a common respiratory pathogen causing significant morbidity, particularly in infants and older adults with comorbidities.
  • Older adults with chronic conditions face an elevated risk of hospitalization from RSV complications.
  • While other viral infections can cause angioedema, RSV-induced uvulitis has not been previously reported.

Purpose of the Study:

  • To report a novel case of uvulitis induced by respiratory syncytial virus (RSV) in an adult patient.
  • To contribute to the understanding of rare RSV manifestations in adults.

Main Methods:

  • Case report detailing a patient's presentation and diagnosis.
  • Clinical observation and diagnostic workup for RSV infection and associated uvulitis.

Main Results:

  • The patient presented with symptoms consistent with RSV infection.
  • The case confirmed RSV as the causative agent for uvulitis in this adult patient.
  • This represents the first documented instance of RSV-induced uvulitis.

Conclusions:

  • Respiratory syncytial virus (RSV) can manifest with rare complications such as uvulitis in adults.
  • This case expands the spectrum of known RSV-related clinical presentations.
  • Further investigation may be warranted to understand the mechanisms and frequency of such rare RSV complications.