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Updated: Jul 9, 2026

Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Complex Chimeric Flap Microsurgery
Z-Hye Lee1, Matthew M Hanasono1, Peirong Yu1
1Department of Plastic Surgery, The University of Texas M.D. Anderon Cancer Center, 1515 Holcombe Boulevard, #1488, Houston, TX 77030, USA.
None:
Extensive and 3-dimensionally complex defects require free flap reconstruction with multiple tissue types. This has traditionally been accomplished with 2 or more free flaps. Recent advancement in perforator anatomy and perforator flaps has enabled us to explore flap options with multiple tissue components based on a single "mother" source vessel: the chimeric flap. A chimeric flap may consist of various combinations of 2 or more fasciocutaneous, muscular/myocutaneous, or osseous flaps with freedom for each tissue component to be separated to cover a complex defect. The design of chimeric flaps based on several vascular systems will be discussed in this article.
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