Radiation Therapy for Prostate Cancer

Radiation therapy (RT) is a cornerstone in the management of prostate cancer, spanning localized, recurrent, and metastatic disease. Advances in technology, fractionation schedules, and combination strategies have expanded the role of RT and improved patient outcomes. Some studies show long-term biochemical control rates reaching above 90% for low-risk and favorable intermediate risk, and rates frequently exceed 75% in less favorable risk patients. Additional uses of radiation include the management of recurrent and oligometastatic disease with favorable outcomes. Lastly, adverse events due to radiation are of concern, but rates of long-term toxicity remain low.