Related Experiment Video
Updated: Jan 10, 2026

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
Published on: May 27, 2011
[Vaccination of individuals undergoing immunosuppressive therapy]
Zitta Barrella Harboe1,2, Peter Henrik Andersen3, Peter Asdahl4
1Lunge- og Infektionsmedicinsk Afdeling, Nordsjællands Hospital, Hillerød.
None:
Protecting individuals undergoing immunosuppressive therapy through vaccination remains a clinical challenge due to the heterogeneity of underlying conditions and immunosuppressive treatments. These patients are at increased risk of severe infections, yet vaccination uptake remains suboptimal. Although vaccine responses may be reduced, this review finds vaccination to be generally safe, except for live attenuated vaccines, which should be avoided due to the risk of severe disease. A structured, multidisciplinary approach to vaccination may enhance uptake and improve protection in this vulnerable patient group.
Related Concept Videos
Tumor Immunotherapy
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

