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Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
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Polysaccharide-Based Chiral Stationary Phases Made with Superficially Porous Silica
Tivadar Farkas1, Bezhan Chankvetadze2
1Institute of Physical and Analytical Chemistry, School of Exact and Natural Sciences, Tbilisi State University, Tbilisi, Georgia.
None:
Polysaccharide-based chiral selectors are in wide use in chiral chromatography, both in the analysis and in the purification of chiral compounds. The use of superficially porous silica (SPS) particles, proven successful in various modes of liquid chromatography, is an obvious opportunity to elevate the performance of polysaccharide-based chiral stationary phases as well. In this chapter, the preparation, characterization, and chromatographic evaluation of chiral stationary phases made by combining superficially porous silica with polysaccharide-based chiral selectors are described.
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