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Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis
Published on: April 26, 2024
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Self-supervised autoencoder network for robust heart rate extraction from noisy photoplethysmogram: Applying blind
Matthew B Webster1, Dongheon Lee2, Joonnyong Lee1
1Mellowing Factory Co. Ltd., Seoul, Republic of Korea.
Computers in Biology and Medicine
|November 22, 2025
Summary
This study introduces a self-supervised multi-encoder autoencoder (MEAE) to separate heartbeat signals from photoplethysmogram (PPG) data. The method enhances heart rate (HR) detection, even in noisy biosignals, without pre-processing.
Area of Science:
- Biomedical Engineering
- Signal Processing
- Artificial Intelligence
Background:
- Biosignals are complex mixtures of physiological events.
- Blind Source Separation (BSS) is crucial for extracting individual signals.
- Photoplethysmogram (PPG) signals are often noisy, challenging heart rate (HR) detection.
Purpose of the Study:
- To develop a self-supervised method for separating heartbeat signals from PPG.
- To enhance the accuracy of heart rate detection in noisy PPG data.
- To apply the method to diverse datasets without pre-processing.
Main Methods:
- A self-supervised Multi-Encoder Autoencoder (MEAE) was proposed for BSS.
- The MEAE was trained on a large, open polysomnography database.
- The trained network was applied to noisy PPG datasets from daily activities and surgical patients.
Main Results:
- The separated heartbeat-related source signal significantly improved HR detection.
- The MEAE demonstrated effectiveness on both noisy daily activity and large surgical datasets.
- No pre-processing or data selection was required for training or application.
Conclusions:
- The proposed MEAE method effectively separates heartbeat signals from PPG.
- This approach enhances HR detection accuracy in challenging biosignal conditions.
- The self-supervised, pre-processing-free MEAE shows significant potential for biosignal BSS.

