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Rapid detection of Streptococcus pyogenes in skin and soft tissue infections using the Abbott ID NOW™ Strep A 2
Jari Karhukorpi1, Kati Hallikainen1
1Eastern Finland Laboratory Centre (ISLAB), Joensuu, Finland.
Abstract:
This study evaluated the performance of the Abbott ID NOW™ STREP A 2, a rapid isothermal nucleic acid amplification test (NAAT), for the detection of Streptococcus pyogenes (S.pyogenes) in non-pharyngeal specimens, primarily from skin and soft tissue infections (SSTIs). A total of 180 non-pharyngeal samples submitted for bacterial culture were analyzed, comprising 120 culture-positive and 60 culture-negative specimens for S. pyogenes. Compared to culture, the ID NOW assay demonstrated a sensitivity of 99.2 % (95 % CI: 95.4-99.98 %) and a specificity of 100.0 % (95 % CI: 94.0-100.0 %). Although the ID NOW STREP A 2 assay is currently approved only for pharyngeal swab specimens, our findings indicate that it may also be a reliable method for detecting S. pyogenes in SSTI samples.

