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Invasive fungal sinusitis by Scedosporium boydii in an immunocompromised patient. A case report
Carla Rey-Suarez1, Paula Caramazana-Lopez2, Iván Fernández-Castro2
1Department of Family and Community Medicine, University Hospital Complex of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.
Abstract:
Invasive fungal sinusitis by Scedosporium spp. is a rare but severe infection in immunocompromised patients. We report an 80-year-old woman with poorly controlled diabetes and chronic corticosteroid use who presented with headache, hearing loss, and facial paralysis. She was ultimately diagnosed with sphenoid sinusitis due to Scedosporium boydii. Management required surgical debridement and prolonged antifungal therapy complicated by drug-induced liver injury. Early diagnosis and multidisciplinary treatment are crucial to improve prognosis in these complex infections.
Insights
Invasive fungal sinusitis caused by Scedosporium boydii is a rare, severe infection. Early diagnosis and multidisciplinary care, including surgery and antifungal therapy, are vital for improving outcomes in immunocompromised patients.
Area of Science:
- Mycology
- Infectious Diseases
- Otolaryngology
Background:
- Invasive fungal sinusitis (IFS) is a severe infection, particularly in immunocompromised individuals.
- Scedosporium species are emerging pathogens causing IFS, often associated with significant morbidity and mortality.
- Risk factors include diabetes mellitus and chronic corticosteroid use, which impair immune function.
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