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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
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Interoception-Based Yoga for Chronic Pain: A Pilot Feasibility Study.

Stephanie Voss1, Ishaan Patel1, Claire Skowron2

  • 1College of Applied Health Sciences, University of Illinois Urbana-Champaign, Urbana, IL, USA.

Global Advances in Integrative Medicine and Health
|November 24, 2025
PubMed
Summary
This summary is machine-generated.

This study found a 6-week yoga intervention targeting interoception (the sense of the internal body state) to be feasible and acceptable for chronic pain patients. Preliminary results suggest yoga may improve interoceptive skills and reduce pain.

Keywords:
chronic paininteroceptionyoga

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Area of Science:

  • Pain Management
  • Mind-Body Interventions
  • Interoception Research

Background:

  • Chronic pain is associated with altered interoception, impacting the ability to detect internal bodily sensations.
  • Interoception, the sense of the body's internal state, is a potential therapeutic target for pain management.
  • The feasibility of yoga interventions targeting interoception in chronic pain populations remains unexplored.

Purpose of the Study:

  • To assess the feasibility and acceptability of a 6-week yoga intervention focused on interoception for individuals with chronic pain.
  • To preliminarily evaluate the intervention's effectiveness on interoceptive sensibility, interoceptive accuracy, pain levels, and psychosocial outcomes.

Main Methods:

  • A single-arm feasibility study design was employed.
  • Participants (N=24) underwent a 6-week interoception-based yoga intervention.
  • Feasibility, acceptability, interoceptive sensibility (MAIA-2), interoceptive accuracy (heartbeat counting), pain, and psychosocial measures were assessed at baseline and post-intervention.

Main Results:

  • The intervention demonstrated feasibility and high acceptability, with 79% of participants completing the study.
  • No serious adverse events were reported.
  • Preliminary analysis indicated statistically significant improvements in interoceptive sensibility, interoceptive accuracy, and pain reduction (p < .05).

Conclusions:

  • The interoception-based yoga intervention is feasible and acceptable for individuals with chronic pain.
  • The intervention shows promise for enhancing interoceptive skills and alleviating pain.
  • Further research is warranted to confirm the efficacy of interoception-focused yoga for chronic pain management.