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Published on: September 20, 2020
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Initial multicenter experience with the Raptor aspiration catheter for treating large vessel occlusion ischemic
Alejandro Venegas1, Keren Zambrano2, Juan Pablo Cruz1,3
1Neuroradiology Department, Instituto de Neurocirugia Dr Asenjo, Santiago, Chile.
Summary
The Raptor catheter shows promise as a safe and effective first-line treatment for mechanical thrombectomy in large vessel occlusion ischemic strokes. This direct aspiration technique achieved high recanalization rates with low complication rates.
Area of Science:
- Neurology
- Interventional Neuroradiology
- Stroke Medicine
Background:
- Mechanical thrombectomy (MT) is the standard treatment for acute ischemic stroke due to large vessel occlusion (LVO).
- Direct aspiration techniques (ADAPT) offer an alternative to stent retrievers (SRs) with comparable efficacy.
- The Raptor catheter's utility as a primary aspiration device in LVO MT requires further investigation.
Purpose of the Study:
- To evaluate the safety and efficacy of the Raptor catheter as a first-line aspiration device for MT in patients with LVO.
- To assess recanalization rates, first-pass effect (FPE), and complication rates associated with Raptor catheter use.
Main Methods:
- A prospective, national multicenter study enrolled 46 patients with acute ischemic stroke and LVO.
- Patients were treated using the Raptor catheter as a first-line ADAPT technique.
- Demographic, clinical, procedural data, and safety/efficacy outcomes were collected and analyzed descriptively.
Main Results:
- The study included 46 patients (mean age 66 years; 39.1% women) with M1 segment LVOs being most common (67.4%).
- First-pass effect (mTICI ≥2c) was achieved in 54.3% of patients, with final recanalization (mTICI ≥2b) in 93.5%.
- Complications occurred in 10.9% of patients, including symptomatic intracranial hemorrhage in 3 cases; 90-day mortality was 6.5%, and 61.9% achieved functional independence.
Conclusions:
- The Raptor catheter demonstrated favorable safety and efficacy as a first-line MT strategy for LVO.
- Recanalization and FPE rates were comparable to existing large-bore aspiration devices.
- Further comparative studies are warranted to confirm these findings and establish the Raptor catheter's role in LVO treatment.

