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Updated: May 2, 2026

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The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
Published on: October 7, 2016
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Preparation of Hydrogel by Crosslinking and Multi-Dimensional Applications.
Md Murshed Bhuyan1, Jae-Ho Jeong2
1Department of Mechanical, Smart, and Industrial Engineering (Mechanical Engineering Major), Gachon University, 1342, Seongnam-daero, Sujeong-gu, Seongnam-si 13120, Republic of Korea.
Gels (Basel, Switzerland)
|November 26, 2025
Summary
Functional hydrogels offer adaptable solutions across diverse fields due to their stimulus-responsive, biodegradable, and self-healing properties. This review explores novel synthesis and applications, enhancing material science and sustainability.
Area of Science:
- Materials Science
- Biomedical Engineering
- Polymer Chemistry
Background:
- Functional hydrogels are advanced materials with significant utility in biomedical engineering, agriculture, pollution control, and electronics.
- Their adaptability and versatility make them crucial for scientific and industrial progress.
- Key properties include stimulus-responsivity, biodegradability, biocompatibility, flexibility, self-healing, and reusability.
Purpose of the Study:
- To explore novel synthesis techniques for functional hydrogels.
- To investigate the multidimensional applications of various hydrogel types.
- To provide a comprehensive overview of hydrogel functionalities and underlying science.
Main Methods:
- Review of existing literature on hydrogel synthesis and modification.
- Analysis of chemical and physical modification strategies for performance enhancement.
- Examination of functional processes and interactions in diverse application sectors.
Main Results:
- Hydrogels exhibit unique stimulus-responsive behaviors (e.g., to light, pH, temperature).
- Biodegradability and biocompatibility are key for ecological and medical uses.
- Self-healing and reusability contribute to sustainability and efficiency.
Conclusions:
- Hydrogel preparation requires precise methods and careful material selection.
- Chemical and physical modifications are essential for optimizing hydrogel performance.
- This review empowers research into new hydrogel applications and optimized uses across sectors.

