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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

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Magnetic Hydrogels as a Treatment for Oncological Pathologies.

Veronica Manescu Paltanea^1,2, Adrian-Vasile Dumitru^3,4, Aurora Antoniac¹

¹Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, District 6, RO-060042 Bucharest, Romania.

Journal of Functional Biomaterials

|November 26, 2025

Summary

Magnetic hydrogels offer innovative cancer therapies, overcoming limitations of traditional nanoparticles. This review explores their applications in hyperthermia, drug delivery, and immunotherapy for improved localized cancer treatment.

Keywords:

cancer treatment controlled drug release immunotherapy magnetic field guidance magnetic hydrogel magnetic hyperthermia oncology saturation magnetization

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Area of Science:

Oncology and Materials Science

Background:

Cancer projected to cause 19 million deaths by 2050, necessitating novel therapeutic strategies.
Existing magnetic nanoparticles have limitations for localized cancer treatment.
Magnetic hydrogels present a promising alternative for targeted oncological applications.

Purpose of the Study:

To review magnetic hydrogels as potential localized cancer therapies.
To discuss synthesis, properties, and applications of magnetic hydrogels in oncology.
To highlight advancements in magnetic hydrogel-based cancer treatment strategies.

Main Methods:

Literature review of magnetic hydrogel synthesis and characterization.
Analysis of in vitro and in vivo studies on magnetic hydrogels for cancer therapy.
Examination of applications including magnetic hyperthermia, drug delivery, and immunotherapy.

Main Results:

Magnetic hydrogels demonstrate potential in magnetic hyperthermia, controlled drug release, and immunotherapy.
Key attributes of ideal magnetic hydrogels for cancer treatment identified.
Integration of magnetic properties and external magnetic fields enhances therapeutic efficacy.

Conclusions:

Magnetic hydrogels show significant promise for advanced, localized cancer treatment.
Further research is needed to address toxicity and optimize future applications.
Future trends include developing novel magnetic hydrogel formulations and treatment combinations.