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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
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Stretched Radial Trajectory Design for Efficient MRI with Enhanced K-Space Coverage and Image Resolution.

Li Song Gong1,2, Zihan Zhou2,3, Qing Li4

  • 1Department of Physics and Astronomy, University of California, Irvine, CA 92697, USA.

Bioengineering (Basel, Switzerland)
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a novel stretched radial trajectory for Magnetic Resonance Imaging (MRI), improving image resolution by expanding k-space coverage without longer scan times. This technique enhances visualization of fine details in structural and quantitative imaging.

Keywords:
low-field MRIquantitative MRIradial MRIsampling trajectory

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Area of Science:

  • Medical Imaging
  • Biophysics
  • Radiology

Background:

  • Magnetic Resonance Imaging (MRI) resolution is crucial for accurate diagnosis.
  • Current methods to improve resolution often require longer scan times or specialized hardware.
  • Expanding k-space coverage is key to enhancing MRI spatial resolution.

Purpose of the Study:

  • To present a stretched radial trajectory design for enhanced MRI spatial resolution.
  • To demonstrate improved k-space coverage without increasing readout duration or scan time.
  • To validate the method's effectiveness in both phantom and in vivo experiments.

Main Methods:

  • Developed a stretched radial trajectory by dynamically modulating gradient amplitudes.
  • Achieved square k-space coverage in 2D and cubic coverage in 3D imaging.
  • Validated using phantom and in vivo experiments on GE and Siemens scanners at 0.55 T and 3 T.

Main Results:

  • Demonstrated improved image sharpness and clearer visualization of fine structures.
  • Point spread function analysis confirmed enhanced resolution.
  • Showcased improved T1 and T2 mapping accuracy in MRF acquisitions.
  • Successfully visualized small phantom details and brain vasculature.

Conclusions:

  • The stretched radial trajectory enhances MRI spatial resolution without additional scan time or hardware.
  • The method is generalizable for both structural and quantitative MRI applications.
  • Suitable for MRI systems with moderate gradient performance.