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Updated: Jul 18, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Dural Injury Revealed by 64 Cu-DOTA PET/CT Cisternography and Intraoperative Detection of a Cholesteatoma After a
Robert Drescher1, Gerlind Schneider2, Christian Senft3
1Clinics of Nuclear Medicine.
Abstract:
A 50-year-old man with a history of a gunshot wound to the skull base in 1997 presented with new secretion from a retroauricular skin defect and clinical signs of a cerebrospinal fluid (CSF) leak. MRI was contraindicated due to retained metallic foreign bodies. [ 64 Cu]Cu-DOTA PET/CT cisternography revealed progressive extravasation of CSF tracer from the posterior fossa toward a mastoid defect, consistent with a CSF leak, but no fistula to the skin. Intraoperative findings confirmed the leak and identified a cholesteatoma within the bullet tract. This case illustrates the complexity of temporal bone gunshot injuries and highlights the diagnostic utility of PET/CT cisternography in detecting CSF leaks.
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