BENIGN FASCICULATION SYNDROME AMONG HEALTH CARE WORKERS, A SINGLE CENTER STUDY

Area of Science:

• Neurology
• Psychiatry

Background:

• Benign Fasciculation Syndrome (BFS) is a neurological disorder characterized by persistent muscle twitching without underlying pathology.
• Unlike conditions like ALS, BFS does not involve muscle weakness or atrophy.
• Psychological factors such as anxiety, depression, and fear of serious illness may contribute to BFS, particularly in healthcare workers.

Purpose of the Study:

• To determine the prevalence and characteristics of BFS in healthcare workers.
• To investigate the correlation between BFS and anxiety, depression, and fear of motor neuron disease (MND) in this population.

Main Methods:

• A comparative cross-sectional study diagnosed BFS based on clinical fasciculations, normal neurological exams, nerve conduction studies (NCS), and electromyography (EMG).
• Anxiety and depression were assessed using the GAD-7 and PHQ-9 scales.
• A comparative group representing the general population was included.

Main Results:

• BFS prevalence was significantly higher in healthcare workers (13.9%) compared to the general population (3.0%), indicating over five times the odds.
• Accompanying symptoms included perceived motor weakness (33.3%), sensory symptoms (26.7%), and tremor (26.7%), with an average symptom duration of over three years.
• A strong association was found between BFS and psychological comorbidities: 60% of BFS patients had anxiety (over half severe), and 33.3% had depression. Anxiety or depression increased BFS risk five-fold in healthcare workers.

Conclusions:

• Healthcare workers are at a significantly elevated risk for Benign Fasciculation Syndrome (BFS).
• High rates of severe anxiety and depression within this cohort are strongly associated with and likely precipitate BFS.
• Integrating psychological screening and mental health support is crucial for managing BFS in healthcare professionals.