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Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

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RADIOGRAPHIC EVALUATION OF THE IMPACT OF PRF MEMBRANE LAYERING ON PERI-IMPLANT TISSUE: RANDOMIZED CONTROLLED CLINICAL

A Kurukchi¹, A Al-Radha¹, A Mahmood¹

¹Department of Oral Surgery and Periodontology, College of Dentistry, Mustansiriyah University, Baghdad, Iraq.

Georgian Medical News

|November 28, 2025

Summary

Platelet-rich fibrin (PRF) membranes, especially multiple layers, improve peri-implant soft tissue thickness and preserve bone height around dental implants. This enhances the long-term success of implant dentistry.

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Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial

Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial

Published on: September 29, 2015

Area of Science:

Dental Implantology
Regenerative Medicine
Biomaterials

Background:

Maintaining peri-implant soft tissue and bone height is crucial for dental implant longevity.
Platelet-rich fibrin (PRF) is a biomaterial used to enhance tissue healing.
The impact of PRF membrane layering on peri-implant tissues requires further investigation.

Purpose of the Study:

To evaluate the effect of single versus multiple layers of PRF membranes on peri-implant tissue phenotype.
To compare PRF membrane application with a control group in enhancing soft tissue thickness and bone height.
To assess the radiographic soft tissue thickness (RSTT) and bone height (BH) at various postoperative intervals.

Main Methods:

A prospective clinical trial involving 45 participants divided into three groups: single PRF, multiple PRF, and control.
Standardized bitewing radiographs were used to measure RSTT and BH pre-procedure and at 6 and 12 weeks post-procedure.
One-way ANOVA was employed for data analysis with a significance level of 0.05.

Main Results:

Both single and multiple PRF groups showed increased RSTT compared to the control group at all measured intervals.
The multiple PRF group exhibited superior retention of vertical bone levels compared to the control group.
PRF application led to enhanced soft tissue thickness and bone preservation around dental implants.

Conclusions:

PRF application significantly improves peri-implant soft tissue thickness.
Multiple layers of PRF membranes are particularly effective in preserving crestal bone height.
PRF shows promise as an adjunct for enhancing the stability and longevity of dental implants.