Related Experiment Video
Updated: Jul 15, 2026
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Progressive Subretinal Fibrosis and Uveitis Associated with Hodgkin Lymphoma
Daniella Socci da Costa1,2, Remo Turchetti Moraes1, Moyses Eduardo Zajdenweber1
1Instituto Brasileiro de Oftalmologia (IBOL), Rio de Janeiro, Brazil.
Introduction:
The aim of this study was to report an unusual case of a presumed paraneoplastic syndrome associated with Hodgkin lymphoma (HL).
Case Presentation:
An otherwise healthy 18-year-old male patient presented with progressive bilateral visual loss over a 2-month period. Fundus examination revealed multiple yellow-whitish lesions in both eyes, resembling multifocal choroiditis. Over time, the patient developed subretinal fibrosis and a palpable cervical lymph node, which was biopsied, confirming the diagnosis of HL.
Conclusion:
Ocular involvement in HL is exceedingly rare and may manifest with a wide range of signs and symptoms. Paraneoplastic inflammatory syndromes should be considered by ophthalmologists in patients with atypical bilateral posterior uveitis.
Related Concept Videos
01:15Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:27Diabetic Retinopathy