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Related Experiment Videos

Autoantibodies mimicking alloantibodies.

P D Issitt, D C Zellner, S D Rolih

    Transfusion
    |November 1, 1977
    PubMed
    Summary

    This study describes a myelofibrosis patient with unusual red blood cell autoantibodies. These antibodies, initially appearing as anti-E and anti-c, were found to be distinct, aligning more closely with the anti-Hr antibody series.

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    Vox sanguinis·1997

    Area of Science:

    • Immunology
    • Hematology
    • Transfusion Medicine

    Background:

    • Myelofibrosis is a bone marrow disorder characterized by fibrosis and extramedullary hematopoiesis.
    • Patients with myelofibrosis can develop multiple red blood cell autoantibodies, complicating transfusion management.
    • Accurate identification of red blood cell antibodies is crucial for preventing transfusion reactions.