Related Experiment Video
Updated: Jan 9, 2026

Author Spotlight: Developing Innovative Therapeutic Strategies for Hemorrhagic Shock Research
Published on: March 22, 2024
Shock-Related Thyroid Changes: A Rare Presentation in a Young Patient With Hemorrhagic Shock Secondary to a Road
Ajit Thakur1, Prashant Bhatia1, Avinash Sharma1
1Critical Care Medicine, Asian Institute of Medical Sciences, Faridabad, IND.
Abstract:
Shock-related thyroid changes are a rare radiological finding, considered part of the hypovolemic shock complex. It is characterized by thyroidal and perithyroidal edema without direct thyroid injury, typically seen in severe trauma. Very few cases have been described in the literature. We report a case of a 15-year-old male who presented in hemorrhagic shock following a road traffic accident. Whole-body computed tomography (CT) imaging demonstrated heterogeneous thyroid enhancement with perithyroidal edema, consistent with shock-related thyroid changes, in the absence of direct thyroid trauma. The patient also sustained a high-grade splenic injury requiring emergent laparotomy and splenectomy, along with orthopedic intervention for a femur fracture. Thyroid function tests were normal, and the patient gradually improved with appropriate surgical and supportive management. The radiological features of shock-related thyroid changes are distinct and must be differentiated from direct thyroid injury or adjacent vascular damage. The underlying pathophysiology is uncertain, but proposed mechanisms include third-spacing of resuscitative fluids or thyroidal hypoperfusion during profound hypovolemia. Recognition of this entity is crucial as it is self-limiting and does not require specific thyroid-directed intervention. Shock-related thyroid changes are a rare but important secondary imaging finding in the setting of severe trauma and hypovolemic shock. Awareness of this condition can help avoid misdiagnosis and unnecessary investigations.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...

