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Updated: Jan 9, 2026
08:56
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
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Risk Factors for Developing Critical Illness Polyneuropathy at a Referral Medical Center in Lebanon: A Prospective
Hassan Doumiati1, Fatima Rawas1, Nisrin Jaafar2
1Neurology, American University of Beirut Medical Center, Beirut, LBN.
Cureus
|December 1, 2025
Summary
Thyroid dysfunction is linked to critical illness polyneuropathy (CIP) in ICU patients. Routine thyroid screening may help identify patients at risk for this neuromuscular complication.
Area of Science:
- Critical Care Medicine
- Neurology
- Endocrinology
Background:
- Critical illness polyneuropathy (CIP) is a frequent neuromuscular complication in critically ill patients.
- CIP is associated with significant morbidity, prolonged mechanical ventilation, and delayed recovery.
Purpose of the Study:
- To identify clinical factors associated with the development or progression of CIP in critically ill patients.
- To investigate the role of thyroid dysfunction in CIP pathogenesis.
Main Methods:
- Prospective cohort study of 70 adult ICU patients.
- Nerve conduction studies (NCS) performed on day 0 and day 7.
- Analysis of clinical variables including demographics, medical history, and medications.
Main Results:
- Nine out of 24 analyzed patients (37.5%) developed new or progressive CIP by day seven.
- Thyroid dysfunction was the only clinical variable significantly associated with CIP development (p = 0.026).
- 32% of CIP patients had underlying hypothyroidism or hyperthyroidism.
Conclusions:
- Thyroid dysfunction is significantly associated with CIP development in critically ill patients.
- Thyroid status may play an underrecognized role in CIP pathogenesis.
- Routine thyroid screening in ICU patients may be beneficial.
Keywords:
critical illness polyneuropathyelectromyography (emg)intensive care unitnerve conduction studiesthyroid dysfunctionMore Related Videos
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