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Updated: Jan 9, 2026

Single-throughput Complementary High-resolution Analytical Techniques for Characterizing Complex Natural Organic Matter Mixtures
Published on: January 7, 2019
CIeaD: A Complementary CID and EAD Mass Spectral Library for Phytochemicals
Yatendra Singh1, Paul C Norris2, Sibesh Maharjan1
1Department of Biology, University of Mississippi, Oxford, Mississippi 38677, United States.
Abstract:
Plant metabolomics faces major challenges in metabolite identification due to the structural diversity of plant metabolites and limited coverage in existing spectral libraries. To address this, we developed CIeaD (Collision-Induced and Electron-Activated Dissociation), an open-access plant metabolite spectral library containing complementary CID and EAD spectra. The library includes curated high-resolution spectra for 2,305 phytochemicals across major metabolite classes, acquired in both positive and negative modes with a dual fragmentation mechanism to capture a wide range of diagnostic ions. CIeaD library is provided in multiple formats and can be accessed at https://www.moleculardetective.org/Links.html.
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