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Related Concept Videos

Lipid Absorption01:24

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Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
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Related Experiment Video

Updated: Jan 9, 2026

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
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Deep Labial Fat Filler Technique for Effective Lip Eversion.

Gi-Woong Hong1, Mariana César Corrêa2, Jong Keun Song3

  • 1Samskin Plastic Surgery Clinic, Seoul, Korea.

The Journal of Craniofacial Surgery
|December 8, 2025
PubMed
Summary

Aging lips can be effectively rejuvenated with a new deep-plane hyaluronic acid filler technique. This anatomy-guided approach restores lip structure and eversion, enhancing natural appearance and reducing complications from superficial overfilling.

Keywords:
Dermal fillershyaluronic acidliprejuvenation

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Area of Science:

  • Plastic Surgery
  • Dermatology
  • Aesthetic Medicine

Background:

  • Lip aging involves fat atrophy and mucosal changes, leading to thinning and inversion.
  • Superficial volumization techniques can obscure natural lip landmarks and fail to achieve eversion.

Purpose of the Study:

  • To present a targeted, anatomy-guided technique for lip augmentation using hyaluronic acid filler.
  • To restore deep structural support and achieve lip eversion while preserving aesthetic landmarks.

Main Methods:

  • Injecting hyaluronic acid filler into the deep suborbicularis oris (deep labial) fat via an intramucosal approach.
  • Utilizing plane-specific delivery with needles for shaping or cannulas for eversion.
  • Emphasizing preprocedure assessment, conservative dosing, and safety measures like avoiding commissural entry points.

Main Results:

  • The deep-plane technique successfully improves vermilion show, border definition, and commissure orientation.
  • Achieves a natural feel and motion with improved lip structure and eversion.
  • Reduces risks of surface irregularity and overprojection associated with superficial techniques.

Conclusions:

  • This deep-plane lip augmentation strategy aligns with fat-compartment aging models.
  • It offers a reproducible method for natural-looking lip rejuvenation and may decrease complications.
  • The technique effectively restores deep structural support for enhanced lip eversion and definition.