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Systemic Conditions and Medication Use in Older Patients Undergoing Dental Implants: A Nationwide Cross-Sectional
Jaeyeon Kim1, Jisun Huh2, Geun U Park3
1Department of Advanced General Dentistry, College of Dentistry, Yonsei University, Seoul, Korea.
Clinical Implant Dentistry and Related Research
|December 9, 2025
Summary
Most older patients undergoing dental implant surgery have systemic diseases. Cerebrovascular and kidney diseases increase implant removal risk, while osteoporosis and antiresorptive agents decrease it.
Area of Science:
- Dental Implantology
- Geriatric Medicine
- Public Health
Background:
- Older patients frequently have systemic diseases, increasing dental implant surgery risks.
- Limited data exist on systemic conditions and medication use in this demographic.
Purpose of the Study:
- To analyze systemic diseases and medication use in older patients undergoing dental implant surgery.
- To identify factors associated with dental implant removal in patients aged 65 and older.
Main Methods:
- Retrospective analysis of 36,957 patients (65+) undergoing 43,171 implant surgeries (2014-2019).
- Data sourced from the National Health Insurance Service-National Sample Cohort database.
- Logistic regression used to determine factors linked to implant removal.
Main Results:
- 89.33% of patients had at least one systemic disease (hypertension, arthritis, diabetes).
- Cerebrovascular and kidney diseases were associated with increased implant removal risk.
- Osteoporosis and antiresorptive agents were linked to decreased implant removal risk.
Conclusions:
- The majority of older patients undergoing implant surgery have comorbidities.
- Specific systemic conditions influence implant removal risk, necessitating careful patient evaluation.
- Emerging medication trends (DOACs, IV bisphosphonates, denosumab) require clinical attention in geriatric implant dentistry.
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