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Updated: Jan 9, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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Recent advance in macrocyclic CDK inhibitors

Jiamin Zheng1, Zhisen Zhang1, Jinxin Liu2

  • 1Department of Medicinal Chemistry, Insilico Medicine Shanghai Ltd., Shanghai, China.

Future Medicinal Chemistry
|December 9, 2025
PubMed
Abstract

Keywords:
Drug designcyclin-dependent kinasesdrug discoverymacrocyclesoncological therapeutics

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