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Updated: Jan 9, 2026

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
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Laparoscopic vs open surgery for complex hepatolithiasis: A retrospective comparative study.

De-Xin Lin1,2, Xin-Bin Zhuo1,3, Gui-Jian Chang1,3

  • 1Department of Hepatobiliary, Pancreatic and Splenic Surgery, Ningde Clinical Medicine of Fujian Medical University, Ningde 352100, Fujian Province, China.

World Journal of Hepatology
|December 10, 2025
PubMed
Summary

Laparoscopic surgery for complex hepatolithiasis shows similar effectiveness to open surgery but with faster recovery and fewer wound infections. This minimally invasive approach offers a safe alternative for patients.

Keywords:
Complex hepatolithiasisLaennec’s capsuleLaparoscopic surgeryLiver resectionSafetySurgical outcomes

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Area of Science:

  • Hepatobiliary surgery
  • Minimally invasive surgery
  • Surgical outcomes

Background:

  • Complex hepatolithiasis management remains challenging.
  • Limited comparative data exists for laparoscopic versus open surgery.
  • Laparoscopic surgery is increasingly adopted for complex hepatolithiasis.

Purpose of the Study:

  • To compare clinical outcomes between laparoscopic and open surgery for complex hepatolithiasis.
  • To evaluate the safety and efficacy of laparoscopic approach.
  • To assess recovery benefits of laparoscopic surgery.

Main Methods:

  • Retrospective cohort study of 80 patients with complex hepatolithiasis.
  • Comparison between laparoscopic (n=40) and open surgery (n=40) groups.
  • Analysis of clinical, intraoperative, and postoperative data using statistical tests.

Main Results:

  • Laparoscopic surgery had longer operative time (250 min vs 207 min) but shorter hospital stay (9 days vs 14 days).
  • Significantly lower wound infection rates in the laparoscopic group (5.0% vs 22.5%).
  • Comparable stone clearance and overall complication rates; one mortality in the open surgery group.

Conclusions:

  • Laparoscopic surgery is a feasible and safe alternative for complex hepatolithiasis.
  • It offers advantages in terms of faster recovery and reduced wound complications.
  • This approach supports improved patient outcomes compared to open surgery.