Distinction of antioxidants using a three-channel colorimetric sensor array constructed with a bimetallic FeCo...

Area of Science:

• Materials Science
• Analytical Chemistry
• Biochemistry

Background:

• Dietary safety is linked to antioxidant content in food.
• Developing sensitive and accurate methods for antioxidant detection is crucial.
• Nanozymes offer promising catalytic properties for biosensing applications.

Purpose of the Study:

• To synthesize two-dimensional (2D) iron/cobalt metal nanosheets (Fe/Co NSs).
• To develop a multi-channel sensor array based on Fe/Co NSs for antioxidant detection.
• To evaluate the sensor array's accuracy, sensitivity, and anti-interference capabilities.

Main Methods:

• Synergistic self-assembly of Fe3+/Co2+ with terephthalic acid to create Fe/Co NSs.
• Utilizing the peroxidase-like activity of Fe/Co NSs as nanozymes.
• Constructing a three-channel sensor array with 3,3',5,5'-tetramethylbenzidine (TMB) and specific wavelengths (370, 456, 654 nm).

Main Results:

• Fe/Co NSs demonstrated excellent peroxidase-like activity.
• The sensor array achieved 100% accuracy in identifying five specific antioxidants.
• Quantitative analysis of antioxidants was accurate within the range of 100 nM–100 μM.
• The sensor array exhibited strong anti-interference properties against other substances.

Conclusions:

• The developed Fe/Co NS-based sensor array is highly effective for accurate antioxidant identification and quantification.
• The sensor array shows significant potential for discriminating unknown antioxidant samples in real-world applications.
• This technology contributes to enhanced food safety and dietary monitoring.