Electro-oxidative [3+2] cycloaddition for the synthesis of 5-selenyltetrazoles
Peng-Fei Huang1, Zhi-Gang Quan1, Ying Peng1
1Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414006, China. pengfeihuang@whu.edu.cn.
Abstract:
5-Selenyltetrazoles, which combine tetrazole scaffolds with organoselenium frameworks, have been widely incorporated into various functional molecules. Herein, we report an environmentally friendly and efficient electrochemical three-component reaction of isonitriles, diselenides and TMSN3 to access 5-selenyltetrazoles under metal-free conditions. Both aliphatic and aryl isonitriles and diselenides are suitable for this strategy at room temperature, showing excellent functional group tolerance and high atom economy.
More Related Videos
10:42Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
07:12Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Related Concept Videos
Cycloaddition Reactions: Overview
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Cycloaddition Reactions: MO Requirements for Thermal Activation
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Preparation and Reactions of Sulfides
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
