Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Favorable safety outcomes of a perioperative propranolol and etodolac regimen in cancer patients in four randomized controlled trials.

Frontiers in pharmacology·2026
Same author

Augmented Reality Based 3D Modelling for Sentinel Lymph Node Localization in Cutaneous Melanoma: A Pilot Study.

Journal of surgical oncology·2026
Same author

Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics.

Nature communications·2026
Same author

A spatial atlas of the healthy human liver from live donors.

Nature·2026
Same author

Transcriptomics of Upper Gastrointestinal Fluids Can Diagnose Pancreatic Ductal Adenocarcinoma.

Cellular and molecular gastroenterology and hepatology·2026
Same author

Preoperative Workup by a Dedicated Geriatric Surgery Service Improves Outcomes in Elderly Patients Undergoing Pancreaticoduodenectomy.

Journal of surgical oncology·2026
Same journal

Emergency Surgical Cricothyrotomy Videos Online: Reliability and Training Quality Evaluation.

The Journal of surgical research·2026
Same journal

Management of Concomitant Traumatic Abdominal Vascular and Gastrointestinal Injuries: A Descriptive Study.

The Journal of surgical research·2026
Same journal

Article Processing Charges in General Surgery Journals: Implications for Equitable Publishing Access in Low-Income and Middle-Income Countries.

The Journal of surgical research·2026
Same journal

Association of Distal Internal Carotid Artery Tortuosity With Carotid Artery Stenting Outcomes.

The Journal of surgical research·2026
Same journal

Appendectomy and Subsequent Type 2 Diabetes - A National Cohort study.

The Journal of surgical research·2026
Same journal

Perceptions and Barriers to Intraoperative Non-technical Skills Feedback in General Surgery: A Mixed-Methods Study.

The Journal of surgical research·2026
See all related articles

Related Experiment Video

Updated: Jan 8, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

766

Limited Axillary Dissection for Substantial Breast Cancer Axillary Tumor Burden.

Yaniv Berger1, Hila Meiri2, Nora Balint-Lahat3

  • 1Breast Surgery Unit, Department of Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Affiliated to the Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.

The Journal of Surgical Research
|December 12, 2025
PubMed
Summary
This summary is machine-generated.

Limited axillary dissection (LAD) shows comparable survival outcomes to standard axillary lymph node dissection (ALND) for breast cancer patients with substantial axillary tumor burden (SATB). Further prospective studies are warranted to confirm these findings for SATB management.

Keywords:
Axillary lymph node dissectionBreast cancerLimited axillary dissectionLocoregional managementPartial axillary dissection

More Related Videos

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.0K
The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

21.1K

Related Experiment Videos

Last Updated: Jan 8, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

766
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.0K
The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

21.1K

Area of Science:

  • Surgical Oncology
  • Breast Cancer Management
  • Axillary Staging

Background:

  • Axillary lymph node dissection (ALND) is standard for substantial axillary tumor burden (SATB) in breast cancer.
  • Limited axillary dissection (LAD) is being explored as a de-escalated approach.

Purpose of the Study:

  • To evaluate the outcomes of LAD (sentinel lymph node sampling or level 1 ALND) in patients with SATB.
  • To compare LAD outcomes with standard ALND and low axillary tumor burden (LATB) patient groups.

Main Methods:

  • Retrospective review of 33 SATB patients undergoing LAD (2011-2020).
  • Exclusion criteria included neoadjuvant chemotherapy or follow-up <1 year.
  • Comparison with matched ALND (n=50) and LATB (n=137) cohorts.

Main Results:

  • 5-year disease-free survival: 95.7% for LAD in SATB.
  • No significant difference in survival outcomes between LAD, ALND, and LATB groups.
  • Higher KI67, larger tumor size, and no adjuvant radiotherapy independently predicted recurrence in node-positive patients.

Conclusions:

  • LAD demonstrates comparable survival outcomes to ALND for SATB patients.
  • LAD outcomes in SATB are also comparable to LATB patients.
  • Prospective investigation of LAD for SATB is recommended.