Photodynamic therapy: An alternative technique to cervical conization for cervical dysplasia
Jeffrey A How1, Amir A Jazaeri1
1Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Med (New York, N.Y.)
|December 13, 2025
Abstract
None:
Predominantly prevalent in women of reproductive age, high-grade cervical dysplasia and its subsequent management can be challenging and significantly impact fertility goals. In a randomized controlled phase III trial, Chen et al. demonstrate that photodynamic therapy with APL-1702 is better than placebo for regression of CIN2 lesions and has a good safety profile; further investigations are warranted before it can enter standard clinical practice.1.


