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Impact of disease severity on physical function in patients with chronic venous insufficiency: A cross-sectional
Wagner Jorge Ribeiro Domingues1, Emely Kércia Santiago de Souza Brandão2, Lenon Corrêa de Souza3
1Graduate Program in Operational Human Performance, Air Force University, Rio de Janeiro, Brazil; Graduate Program in Human Movement Sciences, Universidade Federal do Amazonas, Manaus, Brazil.
Background:
Chronic venous insufficiency (CVI) affects physical function; however, the impact of disease severity on gait, balance, and handgrip strength in patients with CVI remains unclear.
Objective:
To evaluate the impact of the clinical severity of CVI on physical function parameters in patients in less severe stages (CEAP C3-C4) compared to those in more advanced stages of the disease (CEAP C5-C6).
Methods:
This cross-sectional study included 96 patients of both sexes with CVI with Etiology-Anatomy-Pathology (CEAP) C3 to C6. Physical function was measured using the six-minute walk test (6MWT), Short Physical Performance Battery (SPPB), Gait speed (usal and fast) and handgrip strength. The Mann-Whitney U test was applied to compare physical function indicators according to the disease severity of CVI (CEAP C3-C4 and CEAP C5-C6).
Results:
Patients with CVI CEAP C3-C4 walked 68 meters longer compared to individuals with CVI CEAP C5-C6 (451 m vs 383 m; p = 0.001 respectively) and had a higher total score on the SPPB (11 vs 10 points; p = 0.029). For the other tests there were no statistical differences (P > 0.05).
Conclusion:
Therefore, the clinical severity of CVI appears to influence physical function, with patients in less severe stages (CEAP C3-C4) of the disease demonstrating better walking distances and SPPB scores compared with those classified in more advanced stages of the disease (CEAP C5-C6).
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