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Updated: Jan 8, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Oral side effects of dermatologic therapies: A systematic review and meta-analysis
Reem M Alqahtani1, M Alsarrah Ahmad Farhan1, Saud M Almutiari1
1Department of Dermatology, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Abstract:
Dermatologic treatments can produce clinically significant oral side effects that remain poorly quantified. A significant association between dermatologic therapies and oral complications (ES=1.55, 95% CI: 0.94-2.17, p<0.001) is observed, despite high heterogeneity (I2=96%). Retinoids were predominantly associated with cheilitis and xerostomia, immunosuppressants with mucositis and ulcerations, and JAK inhibitors with opportunistic infections. Thus, data shows the necessity of routine oral assessments and preventive strategies to reduce therapy-related morbidity.
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