Identification and Prenatal Evaluation of Suspected Congenital Cataracts: Three Very Different Cases

Congenital cataracts occur in approximately 1 in 5000 live births and may present as an isolated anomaly or as part of a broader constellation of anomalies. Identifying the etiology of congenital cataracts enables accurate prognostic counseling, assessing recurrence risk, and guiding medical management. Detailed fetal anatomy scans, family history, exposure history, and the presence or absence of additional anomalies must be used to help guide diagnostic testing and management. We describe three very different cases of prenatally diagnosed cataracts: congenital cytomegalovirus (CMV) infection, Walker-Warburg syndrome, and a case with a strong family history of congenital cataracts.