Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The PFAS roadmap-Navigating a path together to improved management.

Sustainability science and technology·2026

Same author

A Liquid-Liquid Extraction Method for Measuring Ultrashort PFCAs and Longer-Chain PFAS in Water.

Analytical chemistry·2026

Same author

Presence of Legacy and Emerging PFAS in Human Liver Specimens Banked in the United States from 2000 to 2024.

Environmental science & technology·2026

Same author

Phase 1 Study of KITE-222, an Autologous CLL-1-Directed CAR T-cell Therapy in Patients with Relapsed/Refractory Acute Myeloid Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026

Same author

Novel driver gene MDC1 confers homologous recombination repair deficiency and genomic instability in chemoresistant relapsing ovarian cancer.

Journal of translational medicine·2026

Same author

Characteristics of 'early adopters' of water treatment capacity needed to remove PFAS and other emerging contaminants in the United States.

Environmental science. Processes & impacts·2026

Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026

Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026

Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026

Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026

Same journal

Retraction.

Science (New York, N.Y.)·2026

Same journal

Making time.

Science (New York, N.Y.)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 8, 2026

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Reevaluating PFAS exposure risks from marine fish.

Jennifer Sun¹, Elsie M Sunderland¹

¹Harvard University, Cambridge, MA, USA.

Science (New York, N.Y.)

|December 18, 2025

Summary

This summary is machine-generated.

Global levels of legacy per- and polyfluoroalkyl substances (PFAS) in marine fish show a significant decline. This research utilized modeling to analyze trends in these persistent environmental contaminants.

More Related Videos

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

A Modified QuEChERS-HPLC Method for Detection of Polycyclic Aromatic Hydrocarbons in Zebrafish Embryos Exposed to Fine Particulate Matter

A Modified QuEChERS-HPLC Method for Detection of Polycyclic Aromatic Hydrocarbons in Zebrafish Embryos Exposed to Fine Particulate Matter

Published on: June 13, 2025

Related Experiment Videos

Last Updated: Jan 8, 2026

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

A Modified QuEChERS-HPLC Method for Detection of Polycyclic Aromatic Hydrocarbons in Zebrafish Embryos Exposed to Fine Particulate Matter

A Modified QuEChERS-HPLC Method for Detection of Polycyclic Aromatic Hydrocarbons in Zebrafish Embryos Exposed to Fine Particulate Matter

Published on: June 13, 2025

Area of Science:

Environmental Science
Ecotoxicology
Marine Biology

Background:

Per- and polyfluoroalkyl substances (PFAS) are persistent organic pollutants found globally.
Legacy PFAS, a subset of these chemicals, have accumulated in marine ecosystems.
Concerns exist regarding the long-term impact of PFAS on marine life and human health through seafood consumption.

Purpose of the Study:

To assess the global trends of legacy PFAS concentrations in marine fish.
To understand the environmental fate and transport of legacy PFAS in marine food webs.
To provide data for risk assessment and regulatory strategies concerning PFAS contamination.

Main Methods:

Utilized a global modeling analysis approach.
Incorporated data on PFAS levels, fish biomass, and environmental factors.
Simulated the bioaccumulation and decline of legacy PFAS in marine fish populations.

Main Results:

A significant global decline in legacy PFAS concentrations within marine fish was observed.
The modeling analysis indicated a reduction in bioaccumulation of these persistent chemicals.
Regional variations in decline rates were identified, suggesting localized factors influence PFAS levels.

Conclusions:

Legacy PFAS contamination in marine fish is decreasing on a global scale.
The findings suggest that environmental remediation or reduced input of legacy PFAS may be effective.
Continued monitoring and research are essential to confirm these trends and address emerging PFAS concerns.