Pharmacologic Methods to Reduce Postoperative Bleeding During the First Stage of the Interpolated Forehead Flap...

The most common complication after interpolated forehead flap repair is postoperative bleeding from the pedicle. Reconstructive surgeons should focus on minimizing postoperative bleeding while ensuring the blood supply and integrity of the flap are preserved.

To provide a comprehensive review of the various methods to reduce the risk of bleeding after interpolated forehead flap repair.

A comprehensive literature review of PubMed articles discussing strategies to reduce postoperative bleeding specifically in interpolated forehead flap repair was performed.

A total of 9 unique techniques were apparent from the literature, including use of hydrophilic polymer and potassium ferrate, ferric subsulfate 20% solution, oxidized regenerated cellulose gauze, gelatin sponges, thrombin-based hemostatic agents, aluminum chloride, cyanoacrylate, skin graft, and tranexamic acid.

Reconstructive surgeons should be knowledgeable of the various techniques to reduce bleeding after interpolated forehead flap repair, as bleeding can result in patient dissatisfaction and often requires intervention. Each technique identified in the literature offers its own advantages and drawbacks; its choice should be tailored to the needs of each patient.