Minimally Invasive Micro-Hole Intervention for Wireless Intracranial Pressure Measurement

Area of Science:

• Biomedical Engineering
• Neurosurgery
• Medical Devices

Background:

• Intracranial pressure (ICP) monitoring is crucial for managing brain diseases.
• Current ICP monitoring methods are invasive or lack convenience.
• Existing wireless ICP sensors require significant surgical intervention.

Purpose of the Study:

• To develop a minimally invasive and wireless method for ICP monitoring.
• To overcome the limitations of current invasive and inconvenient ICP monitoring techniques.

Main Methods:

• Utilized ultrasonic vibration-assisted micro-hole craniotomy for skull access.
• Employed cyclic low-power electroablation for precise dura mater ablation.
• Developed a miniaturized wireless capacitive pressure sensor with a micro-cannula.

Main Results:

• Successfully created a high-quality micro-tunnel for brain access.
• Demonstrated effective ICP monitoring in vivo on rabbits.
• The integrated system enables convenient wireless ICP monitoring with minimal invasiveness.

Conclusions:

• The micro-hole intervention method offers a novel approach to wireless ICP monitoring.
• This technique significantly reduces invasiveness compared to traditional methods.
• The developed system provides a convenient and effective solution for ICP monitoring.