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Global Prevalence and Risk Factors of Constipation Among Patients Receiving Haemodialysis: A Systematic Review and
Nga Thi Thuy Nguyen1,2, Nuzul Sri Hertanti2,3, Yeu-Hui Chuang2,4,5
1Faculty of Nursing and Midwifery, Hanoi Medical University, Hanoi, Vietnam.
Journal of Renal Care
|December 22, 2025
Summary
Constipation affects nearly half of patients on haemodialysis globally, with higher rates in Asia. Diabetes and low physical activity are key risk factors, necessitating targeted interventions.
Area of Science:
- Nephrology
- Gastroenterology
- Public Health
Background:
- Constipation is a common issue impacting the quality of life for haemodialysis patients.
- There's a significant gap in systematic reviews and meta-analyses regarding constipation prevalence in this population.
Purpose of the Study:
- To determine the global prevalence of constipation in patients undergoing haemodialysis.
- To identify significant risk factors associated with constipation in this patient group.
Main Methods:
- A systematic review and meta-analysis adhering to PRISMA guidelines.
- Inclusion of 22 studies with 4963 adult haemodialysis patients.
- Analysis using a random-effects model with assessment of heterogeneity, meta-regression, and publication bias.
Main Results:
- The pooled prevalence of constipation among haemodialysis patients was 42.2%.
- The Asian region showed a significantly higher prevalence compared to other regions.
- Diabetes and low physical activity were identified as significant risk factors.
Conclusions:
- Constipation is highly prevalent in haemodialysis patients, particularly in Asia.
- The Rome criteria were the primary diagnostic method used.
- Healthcare providers should implement regular screening and tailored interventions for constipation management.
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