Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioavailability Enhancement: Drug Solubility Enhancement01:16

Bioavailability Enhancement: Drug Solubility Enhancement

197
Body:Bioavailability is a critical factor in determining a drug's effectiveness. It refers to the proportion of a drug that enters the circulation when introduced into the body and is, as a result, able to have an active effect. Enhancing bioavailability is essential for drugs with poor solubility, as it can significantly impact their therapeutic efficacy. Various methods are employed to increase the solubility of drugs, thereby enhancing their bioavailability.Micronization and nanonization are...
197
Bioavailability Enhancement: Drug Permeability Enhancement01:27

Bioavailability Enhancement: Drug Permeability Enhancement

174
Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...
174
Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

596
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
596

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced Transdermal Patches with Folate Nanoparticles: A Breakthrough in Prenatal Supplementation.

European journal of dentistry·2026
Same author

Characterization of bovine-teeth nanoparticles and its effect on BMP-2 expression in periodontitis rat model.

Brazilian oral research·2026
Same author

Efficacy of Synbiotic Maintenance Dose on Cancer Cachexia in Advanced Nasopharyngeal Cancer: A Randomized Controlled Trial.

Journal of food science·2025
Same author

The Effect of Grouper Bone Nano-Calcium (GBN) and Medium-Chain Triglyceride (MCT) Supplementation on the Ovariectomized Rats.

Journal of nutrition and metabolism·2024
Same author

Macrophage Motility in Wound Healing Is Regulated by HIF-1α via S1P Signaling.

International journal of molecular sciences·2021
Same author

Risk characterisation of constituents present in jamu to promote its safe use.

Critical reviews in toxicology·2021

Related Experiment Video

Updated: Jan 8, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

15.5K

Nanoparticle Saltwater Fish Powder and Cell Protein Pathways in Enamel Density Enhancement.

Sandy Christiono1, Islamy Rahma Hutami2, Fourier Dzar Eljabbar Latief3

  • 1Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Islam Sultan Agung, Semarang, Indonesia.

European Journal of Dentistry
|December 23, 2025
PubMed
Summary

This study shows nanoparticle saltwater fish powder significantly boosts amelogenin and FABP-3 levels in fetal mice, promoting better enamel density for tooth mineralization.

More Related Videos

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

10.6K
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
06:16

Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues

Published on: April 26, 2024

1.2K

Related Experiment Videos

Last Updated: Jan 8, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

15.5K
Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

10.6K
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
06:16

Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues

Published on: April 26, 2024

1.2K

Area of Science:

  • Biochemistry
  • Developmental Biology
  • Materials Science

Background:

  • Amelogenin and FABP-3 are crucial proteins in enamel formation and mineralization.
  • Nutritional interventions for enhancing tooth mineralization are of significant interest.
  • The specific effects of nanoparticle saltwater fish powder on fetal tooth development were previously unclear.

Purpose of the Study:

  • To investigate the impact of nanoparticle saltwater fish powder on amelogenin and FABP-3 expression in fetal mice.
  • To evaluate the subsequent effects on fetal enamel density and tooth mineralization.

Main Methods:

  • A randomized experimental study involving 16 pregnant mice divided into control and treatment groups.
  • The treatment group received nanoparticle saltwater fish powder (2.14 mg/mL) orally.
  • Immunohistochemistry (IHC) and micro-computed tomography (µCT) were used to analyze protein expression and enamel density.

Main Results:

  • Significantly increased amelogenin expression (p=0.005) and FABP-3 expression (p=0.038) were observed in the treatment group.
  • Micro-computed tomography revealed a significant increase in enamel density in fetuses exposed to the fish powder (p=0.022).

Conclusions:

  • Nanoparticle saltwater fish powder effectively modulates amelogenin and enhances FABP-3 expression during fetal tooth development.
  • These findings suggest a potential role for this fish powder as a nutritional intervention to promote enamel development and mineralization.