Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Post-Vaccination COVID-19 Infection among Health Care Workers: Description, Determinants, and Event-History Analysis.

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine·2026
Same author

Evaluate clinical outcomes of three single implants with non-splinted crowns and two implants supporting a three unit bridge.

Bioinformation·2026
Same author

The anaesthesiologist's role in heart transplant: An Armed Forces Medical Services perspective.

Medical journal, Armed Forces India·2026
Same author

Comparison of Isolated Balance Exercise Regimen and Conventional Physiotherapy on Lumbar Flexion-Rotation Movement Impairment in Male Patients With Mechanical Low Back Pain.

Musculoskeletal care·2026
Same author

Review of CNN-Based Approaches for Preprocessing, Segmentation and Classification of Knee Osteoarthritis.

Diagnostics (Basel, Switzerland)·2026
Same author

Current status of antimicrobial resistance in Indian healthcare system: combating antimicrobial resistance with precision medicine.

Frontiers in antibiotics·2026

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

Biomarkers.

Ankur Joshi1,2, Dr Neelesh Malviya3, Dr Sapna Malviya4

  • 1MANDSAUR UNIVERSITY, MANDSAUR, India.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary

Vigna radiata and Vigna pilosa extracts show promise in improving cognitive function in Alzheimer's disease models by reducing oxidative stress and neuroinflammation.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Area of Science:

  • Neuroscience
  • Pharmacology
  • Botany

Background:

  • Alzheimer's disease (AD) is a leading cause of dementia, characterized by neurofibrillary tangles and amyloid plaques.
  • Ayurvedic medicine utilizes Vigna radiata and Vigna pilosa for dementia-related conditions.
  • Understanding the neuroprotective potential of these plants is crucial for developing novel AD therapies.

Purpose of the Study:

  • To investigate the neuroprotective effects of Vigna radiata and Vigna pilosa extracts in an amyloid-beta (Aβ) 1-42 induced rat model of Alzheimer's disease.
  • To evaluate the impact of these plant extracts on cognitive function, oxidative stress, and neuroinflammation in AD.

Main Methods:

  • Rats were treated with ethyl acetate extract of Vigna radiata (200mg/kg) and ethanolic extract of Vigna pilosa (400mg/kg) for 21 days post-Aβ1-42 injection.
  • Cognitive behavior was assessed using the radial arm maze and step-through passive avoidance tests.
  • Brain tissues were analyzed for antioxidant parameters, cytokines, and histological changes.

Main Results:

  • Treatment with Vigna radiata and Vigna pilosa extracts significantly improved cognitive performance in rats.
  • The extracts reduced oxidative stress, evidenced by decreased lipid peroxide and nitric oxide levels, and increased antioxidant enzymes.
  • A dose-dependent reduction in neuroinflammation markers was observed, mitigating disease severity.

Conclusions:

  • Vigna radiata and Vigna pilosa extracts demonstrate significant neuroprotective effects against Alzheimer's disease pathology.
  • These benefits are attributed to the mitigation of oxidative stress and neuroinflammation.
  • These findings support the traditional use of these plants and suggest their potential as therapeutic agents for AD.