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Clinical Manifestations.

Emily Q Wang1, Jarod A Joshi1, Catherine Bosyj1

  • 1University of Windsor, Windsor, ON, Canada.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Older adults can improve memory recall by using semantic clustering, a strategy that groups words by meaning. This memory technique benefits individuals regardless of their cognitive reserve, suggesting its potential for widespread use in managing everyday memory challenges.

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Area of Science:

  • Gerontology
  • Neuropsychology
  • Cognitive Psychology

Background:

  • Memory decline in older adults is influenced by internal memory strategies.
  • Cognitive reserve (CR) may influence the spontaneous use of memory strategies.
  • This study investigates CR proxies (education, crystallized intelligence) and their effect on semantic clustering in older adults.

Purpose of the Study:

  • To examine the role of educational attainment and crystallized intelligence in older adults' use of semantic clustering.
  • To determine if CR proxies moderate the relationship between semantic clustering and memory recall.
  • To assess the effectiveness of semantic clustering in improving memory performance in older adults, including those with mild cognitive impairment (MCI).

Main Methods:

  • Analysis of archival data from 185 older adults (normal cognition and MCI).
  • Hierarchical regression and relative weight analyses to assess the impact of education and crystallized intelligence on semantic clustering and recall.
  • Moderation analysis to investigate the interplay between CR proxies, semantic clustering, and delayed recall.

Main Results:

  • Gender and English language background predicted semantic clustering use.
  • Semantic clustering significantly improved memory performance beyond demographic and CR variables.
  • Crystallized intelligence was negatively associated with delayed recall in MCI patients; however, CR proxies did not moderate the positive effect of semantic clustering on delayed recall.

Conclusions:

  • Women and native English speakers were more likely to use semantic clustering, independent of cognitive reserve.
  • Semantic clustering enhances memory performance irrespective of an individual's cognitive reserve level.
  • Teaching internal memory strategies like semantic clustering may help older adults mitigate everyday memory difficulties.