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Clinical Manifestations.

Cecilia Coelho Nogueira1, Tereza Carvalho Braga1, Aline Carvalho Campanha2

  • 1Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

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Summary

Writing errors in Primary Progressive Aphasia (PPA) were analyzed using word and pseudoword dictation. Rule-based errors and graphemic substitutions were most common, informing diagnosis and therapy for PPA patients.

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Area of Science:

  • Neurology
  • Linguistics
  • Psychology

Background:

  • Word and pseudoword dictation aids in characterizing writing errors in Primary Progressive Aphasia (PPA).
  • Few studies have examined written language in dementia, particularly PPA.
  • Understanding these errors can improve diagnosis, classification, and therapeutic strategies.

Purpose of the Study:

  • To analyze, classify, and quantify writing errors in adults with different types of PPA.
  • To utilize word and pseudoword dictation tasks for error analysis.
  • To provide insights into the specific challenges faced by PPA patients in written language production.

Main Methods:

  • Cross-sectional study at a Cognitive and Behavioral Neurology Outpatient Clinic.
  • Analysis of 18 patients diagnosed with PPA using a word and pseudoword dictation protocol.
  • Errors classified into categories like neologisms, regularization, graphemic errors, and accentuation errors, with descriptive statistical analysis.

Main Results:

  • For regular words, errors in rule knowledge were most common (22.8%).
  • Graphemic substitution errors were prevalent in irregular words (19.1%) and pseudowords (32.4%).
  • 18% of words were not written due to task difficulties, irrespective of word type.

Conclusions:

  • Rule-based errors and graphemic substitution are the most frequent writing errors in this PPA sample.
  • Further analysis with an expanded sample size is planned to investigate PPA subtypes.
  • Findings contribute to a better understanding of written language deficits in PPA.