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Mismatch Repair

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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...

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Related Experiment Video

Updated: Jan 7, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

SyBValS: a validation and error resolution service for biological pathway maps

Yusuf Ziya Ozgul¹, Ugur Dogrusoz², Hasan Balci¹

¹i-Vis Research Lab, Computer Engineering Department, Bilkent University, Universiteler Mh, Ankara, 06800, Turkey.

|December 26, 2025

Summary

No abstract available in PubMed .

Keywords:

Bioinformatics tools Biological pathways Graph layout Graph visualization SBGN

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