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Updated: Jul 9, 2026
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
Recent advances in microneedle array-based wearable sensors.
Xinmei Qian1, Sushuang Xia1, Chunxiang Li1
1School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, Key Laboratory of Molecular Design and Green Chemistry of Hunan Provincial Universities, Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers, Xiangtan, 411201, China.
Microneedle array (MNA) wearable sensors offer painless, continuous monitoring of biomarkers in humans and plants. This review highlights their applications and challenges for future digital health and smart agriculture advancements.
Area of Science:
- Biomedical Engineering
- Materials Science
- Agricultural Technology
Background:
- Wearable sensors integrate microneedle array (MNA) technology for minimally invasive, continuous monitoring.
- MNAs enable direct access to tissue fluids for multiplexed biomarker detection in humans and plants.
- Existing reviews lack comprehensive coverage of MNA-based wearable sensors.
Purpose of the Study:
- To review microneedle array structures, fabrication, and working mechanisms.
- To summarize recent advancements in MNA-based wearable sensor applications for health and agriculture.
- To identify current challenges and future potential of MNA wearable sensors.
Main Methods:
- Literature review focusing on microneedle array structures and fabrication.
- Analysis of working principles for MNA-based wearable sensors.
- Synthesis of recent research on applications in health, sports, and plant monitoring.
Main Results:
- MNAs offer painless, continuous, and multiplexed monitoring of biomarkers.
- Applications span human health monitoring, sports analytics, and precision agriculture.
- Key challenges include mechanical strength, biosafety, and miniaturization.
Conclusions:
- MNA-based wearable sensors show significant potential for real-time monitoring.
- Overcoming technical challenges is crucial for widespread adoption.
- Interdisciplinary efforts are needed to advance digital healthcare and smart agriculture.
