Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

443
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
443
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

174
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
174
Aging01:26

Aging

561
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
561
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.1K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

205
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
205
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

4.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Interoperability Moonshot Proposal.

Applied clinical informatics·2026
Same author

Racial and Ethnic Disparities in the Diagnosis and Treatment of Obstructive Sleep Apnea: A Systematic Review.

International journal of environmental research and public health·2026
Same author

Current Evidence on Cardiovascular Risks in Female Obstructive Sleep Apnea.

Sleep medicine clinics·2026
Same author

Variation in Vasoactive Treatment Selection for Cardiogenic Shock: Insights From the Critical Care Cardiology Trials Network (CCCTN).

Circulation. Heart failure·2026
Same author

Aquatic Toxicological Assessment of Solid Pyrolysis Product (SPP) from Synthetic Textile Feedstock Relative to Biochar, Carbon Black, and Activated Carbon.

Environmental science & technology·2026
Same author

Continuous blood pressure monitoring via hemodynamic parameter and pulse transit time derived from capacitive sensing pads.

Physiological measurement·2026
Same journal

Discrepancies Between Subjective and Objective Evaluation of Sleep: Potential Marker for Mild Cognitive Impairment.

Sleep medicine research·2026
Same journal

The development and psychometric evaluation of the Survey of Obstructive Sleep Apnea Functional Health Literacy.

Sleep medicine research·2021
Same journal

The Influence of Obesity on the Association of Obstructive Sleep Apnea and Atrial Fibrillation.

Sleep medicine research·2021
Same journal

Sleep Apnea and Heart.

Sleep medicine research·2020
Same journal

Sleep and Women's Health.

Sleep medicine research·2015
See all related articles

Related Experiment Video

Updated: Jan 7, 2026

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

3.0K

Obstructive Sleep Apnea and Aging: A Narrative Review.

David Brower1, Eric Pan1, William Goss1

  • 1Wellstar Medical College of Georgia, Division of Pulmonary, Critical Care, and Sleep Medicine, Augusta, GA.

Sleep Medicine Research
|December 29, 2025
PubMed
Summary
This summary is machine-generated.

Obstructive sleep apnea (OSA) is common in older adults, increasing sleepiness and disease risk. This review details OSA

Keywords:
AgingContinuous Positive Airway PressureObstructive Sleep Apnea

More Related Videos

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.2K

Related Experiment Videos

Last Updated: Jan 7, 2026

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

3.0K
Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.2K

Area of Science:

  • Sleep Medicine
  • Geriatrics
  • Neurology

Background:

  • Obstructive sleep apnea (OSA) is a prevalent sleep disorder, particularly in aging populations.
  • OSA is linked to increased daytime sleepiness, cardiovascular issues, and neurological conditions.
  • Understanding OSA in the elderly is crucial due to demographic shifts.

Purpose of the Study:

  • To provide a comprehensive review of obstructive sleep apnea in the elderly.
  • To summarize current knowledge on OSA epidemiology, risk factors, and pathophysiology in older adults.
  • To discuss diagnostic challenges, treatment options, and implications for cognitive health.

Main Methods:

  • Literature review summarizing current understanding of OSA in older individuals.
  • Examination of epidemiological data, risk factors (including menopause), and symptomology.
  • Analysis of diagnostic challenges, pathophysiology (anatomical changes, sleep architecture), and treatment modalities.

Main Results:

  • OSA prevalence increases with age, presenting unique challenges in the elderly.
  • Specific risk factors, symptom presentation (e.g., comorbid insomnia), and diagnostic hurdles exist in this population.
  • Treatment effectiveness varies, with CPAP and surgical options discussed.

Conclusions:

  • Obstructive sleep apnea significantly impacts the quality of life for the elderly.
  • This review serves as a resource for sleep medicine physicians on OSA in older adults.
  • Further understanding is needed regarding OSA's role in cognitive decline and Alzheimer's disease.