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Discrepancies Between Subjective and Objective Evaluation of Sleep: Potential Marker for Mild Cognitive Impairment
Valentina Gumenyuk1, Daniel L Murman1, Thomas Roth2
1University of Nebraska Medical Center, Department of Neurological Sciences, 4239 Farnam st, Omaha NE, 68131 USA.
Background And Objective:
Discrepancies between objective and subjective evaluations of sleep efficiency have been observed in individuals with pathological and healthy aging. Objective sleep evaluation using actigraphy has been proposed as a potential tool for the clinical assessment of mild cognitive impairment.
Methods:
Habitual sleep at home was evaluated using actigraphy (objective measure) and sleep diaries (subjective measure) in 45 participants (between 28- and 72-years-old). Participants were divided into four groups by age and by diagnosis (mild cognitive impairment and Alzheimer's disorder). Cognitive and sleep measures were analyzed for comparisons and correlations.
Results:
Significant discrepancies between objective and subjective sleep efficiency were observed in healthy and pathological ages. The MCI group showed the lowest sleep efficiency compared to other groups. Correlation analysis revealed a significant relationship between cognitive impairments and sleep efficiency in MCI and AD groups.
Conclusions:
Objective sleep evaluation, with a particular focus on sleep efficiency, should be considered as a potential marker for MCI.
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