Related Experiment Video
Updated: Jan 7, 2026

08:55
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
3.4K
Risk Factors for Intraocular Pressure Elevation in Steep Trendelenburg Position During Surgery.
Irem Durmus1, Merve Bulun Yediyıldız1, Hulya Yilmaz Ak1
1Departments of Anesthesiology and Reanimation.
Journal of Glaucoma
|December 31, 2025
Summary
The steep Trendelenburg position (STP) significantly increases intraocular pressure (IOP) during total laparoscopic hysterectomy (TLH). This effect is more pronounced in patients with a high body mass index (BMI).
Area of Science:
- Ophthalmology
- Anesthesiology
- Surgical Innovation
Background:
- Intraocular pressure (IOP) monitoring is crucial during surgical procedures.
- The steep Trendelenburg position (STP) is utilized in various surgeries, including total laparoscopic hysterectomy (TLH).
- Potential impacts of STP on IOP require thorough investigation.
Purpose of the Study:
- To assess the effect of STP on IOP during TLH.
- To explore correlations between IOP changes and patient factors (age, BMI, iridocorneal angle) and surgical duration.
Main Methods:
- Ophthalmologic evaluation and IOP measurements at multiple time points before, during, and after TLH.
- Handheld contact tonometer used for IOP assessment.
- Recording of surgery duration and patient demographics.
Main Results:
- IOP was significantly elevated at all measured time points compared to baseline.
- No significant correlation found between age or iridocorneal angle and IOP.
- A positive correlation between IOP and BMI, and a negative correlation between IOP and surgical duration were observed at the end of surgery.
Conclusions:
- STP significantly increases IOP during TLH.
- Higher BMI is associated with a more pronounced IOP elevation.
- Identifying high-risk patients can inform strategies to mitigate ocular complications.
Related Concept Videos
Glaucoma: Overview
1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Angle Closure Glaucoma: Treatment
1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K
Open Angle Glaucoma: Treatment
920
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
920

