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Congenital insensitivity to pain with anhidrosis: a case report

Natalie Lenggenhager-Krakoski1, Anne Coakley, Hassan Murtaza

  • 1From the Department of Anaesthesiology, Intensive Care and Pain Medicine, Cork University Hospital, Cork City, Ireland (NL-K, AC, HM, BOB).

European Journal of Anaesthesiology
|January 2, 2026
PubMed

Insights

Congenital Insensitivity to Pain with Anhidrosis (CIPA) is a rare condition impacting anesthesia. This report details the first British Isles case in a child requiring surgery, highlighting anesthetic considerations.

Area of Science:

  • Anesthesiology
  • Genetics
  • Pediatric Surgery

Background:

  • Congenital Insensitivity to Pain with Anhidrosis (CIPA) is a rare genetic disorder.
  • CIPA is characterized by the inability to feel pain and anhidrosis (inability to sweat).
  • Perioperative management of CIPA patients presents unique challenges for anesthesiologists.

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